Control of ovulation in mice by progesterone receptor-regulated gene networks
نویسندگان
چکیده
منابع مشابه
Control of ovulation in mice by progesterone receptor-regulated gene networks.
The mid-cycle surge of luteinizing hormone (LH) induces ovulation, a process during which a fertilizable oocyte is released from a mature ovarian follicle. Although ovulation is a physiologically well-characterized event, the underlying molecular pathways remain poorly understood. Progesterone receptor (PGR), which mediates the biological effects of the steroid hormone progesterone, has emerged...
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The progesterone receptor (PGR) is a nuclear receptor transcription factor that is essential for female fertility, in part due to its control of oocyte release from the ovary, or ovulation. In all mammals studied to date, ovarian expression of PGR is restricted primarily to granulosa cells of follicles destined to ovulate. Granulosa cell expression of PGR is induced by the pituitary Luteinizing...
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ژورنال
عنوان ژورنال: Molecular Human Reproduction
سال: 2009
ISSN: 1360-9947,1460-2407
DOI: 10.1093/molehr/gap082